Not particularly amused
I get that it's supposed to be all funny and everything, and offensive Newgrounds content is widely accepted as the norm, but when you say it's based on true events it makes me think you actually were cruel and insensitive to someone just because they had herpes. Herpes is extremely common. I myself get cold sores from time to time, and they're usually barely visible. I just make sure I don't kiss anyone while they're active. Although if I knew they already had herpes then it would be okay.
So yeah. Stuff like racist humor can be seen as making fun of racism or whatever. But this doesn't seem like you're making fun of cruel and insensitive people. It just seems like you are a cruel and insensitive person. I hope I'm wrong though.